Joseph Molnar Selected Research

Thioridazine (Mellaril)

3/2014	Mechanisms by which thioridazine in combination with antibiotics cures extensively drug-resistant infections of pulmonary tuberculosis.
12/2013	The mechanism by which the phenothiazine thioridazine contributes to cure problematic drug-resistant forms of pulmonary tuberculosis: recent patents for "new use".
11/2013	Effect of thioridazine stereoisomers on the drug accumulation of mouse lymphoma and human prostate cancer cell lines in vitro.
9/2012	Why and How the Old Neuroleptic Thioridazine Cures the XDR-TB Patient.
8/2012	Why and how thioridazine in combination with antibiotics to which the infective strain is resistant will cure totally drug-resistant tuberculosis.
3/2012	Potential therapy of multidrug-resistant and extremely drug-resistant tuberculosis with thioridazine.
12/2011	Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 and inhibits the expression of P-glycoprotein.
5/2011	Effective therapy with the neuroleptic thioridazine as an adjunct to second line of defence drugs, and the potential that thioridazine offers for new patents that cover a variety of "new uses".
6/2010	Therapy Of XDR TB with thioridazine a drug beyond patent protection but eligible for patent "as new use".
7/2005	The in vitro activity of phenothiazines against Mycobacterium avium: potential of thioridazine for therapy of the co-infected AIDS patient.

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Joseph Molnar Research Topics

Disease

27	Neoplasms (Cancer) 06/2018 - 03/2002
19	Lymphoma (Lymphomas) 01/2017 - 09/2002
12	Infections 03/2014 - 03/2003
8	Extensively Drug-Resistant Tuberculosis 03/2014 - 05/2009
4	Pulmonary Tuberculosis 03/2014 - 03/2003
4	Tuberculosis (Tuberculoses) 08/2012 - 03/2003
3	T-Cell Lymphoma (Lymphoma, T Cell) 01/2016 - 05/2003
3	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2013 - 07/2010
3	Breast Neoplasms (Breast Cancer) 05/2013 - 01/2009
2	Wounds and Injuries (Trauma) 01/2020 - 04/2009
2	Bacterial Infections (Bacterial Infection) 02/2013 - 09/2007
2	Acquired Immunodeficiency Syndrome (AIDS) 03/2012 - 07/2005
2	Carcinoma (Carcinomatosis) 10/2011 - 05/2005
2	Lung Neoplasms (Lung Cancer) 02/2010 - 01/2007
1	Alzheimer Disease (Alzheimer's Disease) 06/2018
1	Prostatic Neoplasms (Prostate Cancer) 11/2013
1	Psychotic Disorders (Schizoaffective Disorder) 12/2011
1	Colonic Neoplasms (Colon Cancer) 10/2011
1	Carcinogenesis 02/2010
1	Cicatrix (Scar) 04/2009
1	Atrioventricular Block 06/2007
1	Necrosis 11/2005
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2005

Drug/Important Bio-Agent (IBA)

13	Pharmaceutical PreparationsIBA 01/2016 - 05/2003
12	Anti-Bacterial Agents (Antibiotics)IBA 03/2014 - 09/2002
11	Thioridazine (Mellaril)FDA LinkGeneric 03/2014 - 11/2004
9	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 11/2016 - 11/2005
8	Antipsychotic Agents (Antipsychotics)IBA 03/2014 - 03/2002
8	phenothiazineIBA 03/2014 - 03/2002
4	Rhodamine 123IBA 01/2016 - 11/2009
4	PhenothiazinesIBA 02/2013 - 03/2003
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 06/2018 - 11/2009
3	DiterpenesIBA 12/2014 - 06/2006
2	FlavonoidsIBA 01/2016 - 01/2009
2	Ethidium (Ethidium Bromide)IBA 01/2016 - 03/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2014 - 10/2011
2	Adenosine Triphosphate (ATP)IBA 11/2013 - 11/2009
2	1,3- dimethyl- 1,3- (4- fluorophenyl)- 1,3- (3- butyl- (1- piperazinyl)propyl)- 1,3- disiloxaneIBA 05/2013 - 03/2008
2	1,3- dimethyl- 1,3- p- fluorophenyl- 1,3- (3- morpholinopropyl)- 1,3- disiloxaneIBA 05/2013 - 03/2008
2	HydantoinsIBA 03/2012 - 10/2011
2	Chlorpromazine (Thorazine)FDA Link 12/2011 - 11/2004
2	AntigensIBA 02/2010 - 01/2007
2	multidrug resistance-associated protein 1IBA 11/2009 - 01/2009
1	C.I. direct red 80IBA 01/2020
1	HydrogelsIBA 01/2020
1	CollagenIBA 01/2020
1	Cytotoxins (Cytolysins)IBA 06/2018
1	Amyloid (Amyloid Fibrils)IBA 06/2018
1	Amyloid beta-PeptidesIBA 06/2018
1	Memantine (Namenda)FDA Link 06/2018
1	Chlorogenic AcidIBA 01/2017
1	cucurbitaneIBA 11/2016
1	TriterpenesIBA 11/2016
1	screlotiumolIBA 01/2016
1	3,3'-diethyloxacarbocyanineIBA 01/2016
1	CarbocyaninesIBA 01/2016
1	Coloring Agents (Dyes)IBA 01/2016
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2016
1	Drug CombinationsIBA 12/2014
1	BromidesIBA 11/2013
1	Epstein-Barr virus early antigenIBA 05/2013
1	Neoplasm Antigens (Tumor Antigens)IBA 05/2013
1	MorpholinosIBA 05/2013
1	disiloxaneIBA 05/2013
1	Antineoplastic Agents (Antineoplastics)IBA 12/2011
1	AlkaloidsIBA 06/2011
1	Rifampin (Rifampicin)FDA LinkGeneric 05/2011
1	4'-hydroxy-3,3',4-trimethoxylignanIBA 02/2010
1	dihydroguaiaretic acidIBA 02/2010
1	cubebinIBA 02/2010
1	LignansIBA 02/2010
1	hinokininIBA 02/2010
1	talaumidinIBA 02/2010
1	heliobuphthalminIBA 02/2010
1	Proteins (Proteins, Gene)FDA Link 11/2009
1	AnthracyclinesIBA 07/2009
1	SaponinsIBA 07/2009
1	1,3- dimethyl- 1,3- bis(4- fluorophenyl)- 1,3- bis(3- (1- (4- butypiperazinyl))propyl)disiloxaneIBA 05/2009
1	EnzymesIBA 05/2009
1	Silicon CompoundsIBA 03/2008
1	Diclofenac (SR 38)FDA LinkGeneric 09/2007
1	Tetracycline (Achromycin)FDA LinkGeneric 07/2007
1	Nifedipine (Adalat)FDA LinkGeneric 06/2007
1	Methanol (Carbinol)IBA 01/2007
1	jolkinol BIBA 01/2007
1	lathyraneIBA 01/2007
1	PolyestersIBA 06/2006
1	phenoxazineIBA 01/2006
1	BenzoxazolesIBA 11/2005
1	BenzoxazinesIBA 11/2005
1	Heterocyclic Compounds (Compounds, Heterocyclic)IBA 11/2005
1	Carotenoids (Carotene)IBA 05/2005
1	AcetoneIBA 05/2005

Therapy/Procedure

16	Therapeutics 03/2014 - 03/2003
5	Drug Therapy (Chemotherapy) 06/2018 - 05/2003
2	Chemoprevention 05/2013 - 02/2010
1	Fasciotomy 04/2009
1	Skin Transplantation (Skin Grafting) 04/2009
1	Length of Stay 04/2009
1	Negative-Pressure Wound Therapy 04/2009